reference.comThese tails are subject to a number of put up-translational covalent modifications, together with acetylation, phosphorylation, ubiquitination, sumoylation and methylation (reviewed in 1 ). Methylation been discovered on a variety of lysine residues in numerous histones: K4 (utilizing the single-letter amino-acid code for lysine), K9, K27, Lawyer article K36 and K79 in histone H3, K20 in histone H4, K59 in the globular area of histone H4 2 and K26 of histone H1B three Several proteins accountable for the methylation of particular residues have been characterised, and all but one in all these comprises a SET domain